Somewhere in deep space the starship Karma has been hijacked - with the vice-president of the Tedan Tippedai Corporation and a mysterious cargo aboard. Iria, an apprentice bounty hunter, accompanies her brother, Gren, and his boss, Bob, on a rescue mission before the authorities arrive. The extraction turns deadly when it is revealed that the cargo is Zeiram. The Teddan Tippedai Corporation secretly attempted to import the monster to be developed into a powerful, new bio-weapon.